Estradiol Inserts

Low-Dose Vaginal Estrogen for Intimate Health

Vaginal estradiol inserts are a low-dose, bioidentical form of estrogen designed specifically to treat vaginal and urinary symptoms of menopause. Unlike pills, patches, or gels that provide systemic (whole-body) hormone therapy, these small inserts deliver estrogen directly to vaginal tissues where it's needed most, with minimal absorption into your bloodstream.

As you approach and go through menopause, declining estrogen levels cause changes to your vaginal and urinary tract tissues. This leads to uncomfortable symptoms like vaginal dryness, irritation, painful intercourse, and urinary issues. Vaginal estradiol restores moisture and elasticity to these tissues, relieving discomfort and improving your intimate well-being.

What Makes Vaginal Estrogen Different?

Local Treatment, Not Systemic

Delivers estrogen directly to vaginal tissues

Minimal absorption into bloodstream (very low systemic levels)

Focuses specifically on vaginal and urinary symptoms

Different risk profile than systemic hormone therapy

Does NOT treat hot flashes or night sweats

Low-Dose Therapy

10mcg is a low dose designed for vaginal symptoms only

Much lower dose than systemic estrogen products

Effective for local symptoms with minimal systemic effects

Often considered safer for women who cannot take systemic hormones

How Vaginal Estradiol Works

When you insert the small tablet vaginally:

The tablet dissolves and releases estradiol directly to vaginal tissues

Estrogen restores moisture, elasticity, and blood flow to vaginal walls

It thickens vaginal tissue and increases natural lubrication

Benefits extend to urinary tract tissues as well

Minimal hormone enters your bloodstream

Benefits of Vaginal Estrogen

Relieves vaginal dryness – restores natural moisture

Reduces painful intercourse – improves comfort during intimacy

Eliminates vaginal irritation and itching – soothes sensitive tissues

Supports urinary health – may reduce urgency, frequency, and recurrent UTIs

Restores vaginal pH – helps maintain healthy vaginal environment

Improves intimate quality of life – addresses symptoms that affect relationships and well-being

Understanding Local vs. Systemic Estrogen Therapy

It's important to understand the difference between vaginal (local) estrogen and systemic estrogen therapy:

Vaginal Estrogen (Local Treatment)

What it treats: Vaginal dryness, painful intercourse, urinary symptoms

Where it works: Primarily in vaginal and urinary tissues

Absorption: Minimal systemic absorption into bloodstream

What it does NOT treat: Hot flashes, night sweats, mood changes

Dose: Very low dose (10mcg)

Who it's for: Women with vaginal symptoms only, or women who cannot take systemic hormones

Systemic Estrogen (Pills, Patches, Gels)

What it treats: Hot flashes, night sweats, mood changes, bone loss, AND vaginal symptoms

Where it works: Throughout your entire body

Absorption: Full systemic absorption into bloodstream

Dose: Higher doses for whole-body effects

Who it's for: Women with multiple menopausal symptoms

Which Do You Need?

If you ONLY have vaginal symptoms (dryness, painful intercourse)

Vaginal estrogen may be right for you

if you have hot flashes, night sweats, OR multiple symptoms

Systemic estrogen therapy may be more appropriate

If you have both systemic and vaginal symptoms

You may benefit from systemic hormone therapy, which often helps vaginal symptoms too, though some women need both

Who May Benefit from Vaginal Estradiol Inserts

Vaginal estradiol may be appropriate for women experiencing vaginal or urinary symptoms of menopause. Your healthcare provider will evaluate whether this treatment is right for you.

Vaginal Symptoms:

Experience vaginal dryness or irritation

Have painful intercourse (dyspareunia)

Notice vaginal burning, itching, or discomfort

Feel vaginal tightness or lack of elasticity

Have vaginal bleeding or spotting after intercourse due to tissue thinness

Experience general discomfort in the vaginal area

Urinary Symptoms:

Have urinary urgency or frequency

Experience recurrent urinary tract infections

Notice urinary discomfort or burning

Have stress incontinence symptoms

General Suitability

Are in perimenopause, menopause, or postmenopause

Want to address vaginal symptoms specifically

Do NOT have significant hot flashes or other systemic symptoms (or those are controlled)

Prefer local treatment over systemic hormone therapy

Cannot take or prefer not to take systemic hormones

Are looking for the lowest-dose approach to vaginal symptoms

Ideal Candidates

Vaginal estradiol works particularly well for women who:

Have vaginal symptoms as their primary concern

Want to avoid systemic hormone therapy

Have health conditions that make systemic estrogen inappropriate

Prefer targeted, low-dose treatment

Have tried over-the-counter lubricants without adequate relief

Are committed to regular use (initially frequent, then maintenance dosing)

Who Should NOT Use Vaginal Estradiol

Are pregnant or may become pregnant

Have undiagnosed vaginal bleeding

Have a history of breast cancer (in most cases, though some exceptions exist)

Have known or suspected estrogen-dependent cancers

Have a history of blood clots, stroke, or heart attack (though risk may be lower with vaginal estrogen)

Have active liver disease

Are allergic to estradiol or insert ingredients

Medical Evaluation Required:

Your provider will need to:

Evaluate your specific vaginal and urinary symptoms

Review your complete medical and family history

Discuss your risk factors and medical conditions

Determine if vaginal estrogen is appropriate and safe for you

Establish proper dosing schedule (loading phase, then maintenance)

What to Expect with Estradiol Gel Treatment

Week 1: Initial Treatment

Begin daily application (initial phase)
Get comfortable with insertion technique
Symptoms may not improve immediately
You may notice slight vaginal discharge (dissolved tablet) in the hours following insertion - using before bed can minimize these issues
Vaginal tissues begin receiving estrogen

Week 2: Early Changes

Continue daily insertion
Slight improvement in vaginal moisture
Reduced irritation and discomfort
Tissues beginning to respond to estrogen
Painful intercourse may start to improve

Week 3-4: Transition To Maintenance

Typically reduce to twice-weekly dosing
Noticeable improvement in vaginal dryness
Significant reduction in discomfort and irritation
Intercourse becoming more comfortable
Vaginal tissues healthier and more elastic

Month 2-3: Continued Improvement

Maintain twice-weekly dosing schedule
Maximum relief from vaginal symptoms
Comfortable, pain-free intercourse
Vaginal moisture and elasticity restored
Urinary symptoms improving if present
Overall intimate quality of life enhanced

Long-Term (3+ Months):

Sustained symptom relief with continued maintenance use
Twice-weekly dosing maintains healthy vaginal tissues
Continued comfort and intimate well-being
Regular monitoring with your provider

Individual Notes:

Tissue Restoration Takes Time: Vaginal tissues don't recover overnight. Several weeks of consistent use are needed to rebuild healthy tissue.

Maintenance is Essential: Once symptoms improve, continued use at maintenance dose is necessary to keep tissues healthy. Stopping will result in symptoms returning.

Individual Variation: Some women notice improvement quickly, others take longer. Age, severity of atrophy, and individual response all affect timeline.

Why Choose Vaginal Estradiol Inserts?

Targeted Local Treatment: Delivers estrogen exactly where you need it – in vaginal tissues – with minimal systemic absorption. Addresses symptoms at the source.

Low-Dose Approach: Very low dose (10mcg) designed specifically for vaginal symptoms. Often considered for women who cannot or prefer not to take systemic hormones.

Highly Effective for Vaginal Symptoms: Wear your patch while showering, swimming, exercising, and sleeping. Stays on during normal activities so you can live your life.

Small and Discreet: Tiny insert is easy to use and unnoticeable. Private treatment for intimate symptoms.

Convenient Maintenance Schedule: After initial daily dosing, maintenance is just twice weekly. Simple to fit into your routine.

Different Risk Profile: Minimal systemic absorption may mean lower risks compared to systemic hormone therapy (though not risk-free).

May Be Option When Systemic HT Isn't: Some women who cannot take systemic hormones may be able to use low-dose vaginal estrogen under medical supervision.

Improves Intimate Quality of Life: Addresses symptoms that significantly impact relationships, intimacy, and daily comfort. Restores confidence.

May Help Urinary Symptoms: Can improve urinary frequency, urgency, and reduce recurrent UTIs in some women.

Important Considerations:

Vaginal insertion required (though most women find this easy)

Initial daily dosing period (2 weeks typically)

Does NOT treat hot flashes, night sweats, or other systemic symptoms

Some women experience minor vaginal discharge from dissolved tablet

Continued use necessary to maintain benefits

Takes several weeks to see full results

Compassionate Care for Intimate Health at Get Thin MD

Licensed Medical Providers

Experienced healthcare providers who understand the impact of vaginal symptoms on your quality of life and can provide judgment-free care

Personalized Treatment Plans

Customized approach based on your specific vaginal and urinary symptoms, medical history, and treatment goals

Risk Assessment

Thorough evaluation to determine if vaginal estrogen is appropriate and safe for your situation

Direct Delivery from U.S. based Pharmacies

Your medication shipped discreetly to your door in unmarked packaging – 3-month supply

Convenient Online Consultations

Discuss intimate symptoms privately from home through our secure, HIPAA-compliant platform

Clear Usage Instructions:

Detailed guidance on how to use vaginal inserts comfortably and effectively

Ongoing Monitoring

Regular check-ins to assess symptom relief, adjust treatment, and ensure optimal intimate health

Multiple Delivery Options

If vaginal inserts aren't right for you, we can discuss other options including vaginal creams or rings

Frequently Asked Questions

Still have questions? Send us a message

Vaginal Estradiol Inserts for Intimate Comfort

Trusted by Women Like You

Low-Dose Vaginal Estrogen for Intimate Health

What Makes Vaginal Estrogen Different?

Local Treatment, Not Systemic

Low-Dose Therapy

How Vaginal Estradiol Works

Benefits of Vaginal Estrogen

Understanding Local vs. Systemic Estrogen Therapy

Vaginal Estrogen (Local Treatment)

Systemic Estrogen (Pills, Patches, Gels)

Which Do You Need?

If you ONLY have vaginal symptoms (dryness, painful intercourse)

if you have hot flashes, night sweats, OR multiple symptoms

If you have both systemic and vaginal symptoms

Who May Benefit from Vaginal Estradiol Inserts

Vaginal Symptoms:

Urinary Symptoms:

General Suitability

Ideal Candidates

Who Should NOT Use Vaginal Estradiol

Medical Evaluation Required:

What to Expect with Estradiol Gel Treatment

Week 1: Initial Treatment

Week 2: Early Changes

Week 3-4: Transition To Maintenance

Month 2-3: Continued Improvement

Long-Term (3+ Months):

Individual Notes:

Why Choose Vaginal Estradiol Inserts?

Important Considerations:

Compassionate Care for Intimate Health at Get Thin MD

Licensed Medical Providers

Personalized Treatment Plans

Risk Assessment

Direct Delivery from U.S. based Pharmacies

Convenient Online Consultations

Clear Usage Instructions:

Ongoing Monitoring

Multiple Delivery Options

Begin Your Menopause Treatment Journey

Complete Your Assessment

Provider Evaluation

Personalized Treatment Plan

Medication Delivery

Begin Treatment

Follow-Up Care

Frequently Asked Questions

How long until I feel better?

How often do I use the inserts?

Will this help my hot flashes?

Is it difficult to insert?

Will my partner feel it during intercourse?

Can I have intercourse while using this?

Will it leak or cause discharge?

Do I need progesterone with this?

Is vaginal estrogen safer than pills or patches?

Can I use this if I've had breast cancer?

What if I have a hysterectomy?

How long can I use vaginal estrogen?

What if I miss a dose?

Will symptoms come back if I stop?

Can I use lubricants too?